\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Tubulin alpha-4A chain

UniprotKB/SwissProt ID: P68366 (P68366)

Gene Name: TUBA4A

Organism: Homo sapiens (Human)

Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002452 Alpha_tubulin
IPR008280 Tub_FtsZ_C
IPR000217 Tubulin
IPR037103 Tubulin/FtsZ-like_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR023123 Tubulin_C
IPR017975 Tubulin_CS
IPR003008 Tubulin_FtsZ_GTPase

The S-nitrosylation sites of P68366

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 295 QLSVAEITNA C FEPANQMVKC  CCCEEEEEEH H HHHHHCHHHH  4.27% 20140087
37478858
2 315 CDPRHGKYMA C CLLYRGDVVP  CCCEEEEEEH H HHHHHCHHHH  0.67% 37478858
3 316 DPRHGKYMAC C LLYRGDVVPK  CCCEEEEEEH H HHHHHCHHHH  1.81% 37478858
4 347 TKRSIQFVDW C PTGFKVGINY  CCCEEEEEEH H HHHHHCHHHH  1.55% 20140087
19483679
37478858
5 376 GDLAKVQRAV C MLSNTTAIAE  CCCEEEEEEH H HHHHHCHHHH  1.9% 20140087
19483679
37478858
6 54 GGDDSFTTFF C ETGAGKHVPR  CCCEEEEEEH H HHHHHCHHHH  3.9% 20140087