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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 14-3-3 protein theta

UniprotKB/SwissProt ID: P68254 (P68254)

Gene Name: Ywhaq

Organism: Mus musculus (Mouse)

Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1 (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000308 14-3-3
IPR023409 14-3-3_CS
IPR036815 14-3-3_dom_sf
IPR023410 14-3-3_domain
IPR042584 14-3-3_theta

The S-nitrosylation sites of P68254

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 134 DYFRYLAEVA C GDDRKQTIEN  CCHHHHHHHH H HHHHHHHHHH  8.09% 19101475
21278135
2 25 QAERYDDMAT C MKAVTEQGAE  CCHHHHHHHH H HHHHHHHHHH  1.59% 24926564
20925432
3 94 EKVESELRSI C TTVLELLDKY  CCHHHHHHHH H HHHHHHHHHH  2.48% 22588120