Protein Name:
Tropomyosin alpha-4 chain
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UniprotKB/SwissProt ID: P67936 (P67936)
Gene Name:
TPM4
Organism: Homo sapiens (Human)
Function: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments (By similarity). Binds calcium (PubMed:1836432). Plays a role in platelet biogenesis
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P67936
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
154 |
EERAEVSELK C GDLEEELKNV |
CCCHHHHHHH H HHHHHHHHHH |
8.84% |
20140087
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| 2 |
247 |
TLDQTLNELN C I--------- |
CCCHHHHHHH H HHHHHHHHHH |
6.45% |
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