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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Casein kinase II subunit beta

UniprotKB/SwissProt ID: P67874 (P67874)

Gene Name: Csnk2b

Organism: Rattus norvegicus (Rat)

Function: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (PubMed:16818610). Participates in Wnt signaling (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016149 Casein_kin_II_reg-sub_N
IPR035991 Casein_kinase_II_beta-like
IPR000704 Casein_kinase_II_reg-sub

The S-nitrosylation sites of P67874

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 109 EKYQQGDFGY C PRVYCENQPM  CCCHHHHHHH H HHHCCCCCEE  1.45% 21278135
2 114 GDFGYCPRVY C ENQPMLPIGL  CCCHHHHHHH H HHHCCCCCEE  3.47% 21278135