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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Actin, cytoplasmic 2

UniprotKB/SwissProt ID: P63261 (P63261)

Gene Name: ACTG1

Organism: Homo sapiens (Human)

Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. May play a role in the repair of noise-induced stereocilia gaps thereby maintains hearing sensitivity following loud noise damage (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR004000 Actin
IPR020902 Actin/actin-like_CS
IPR004001 Actin_CS
IPR043129 ATPase_NBD

The S-nitrosylation sites of P63261

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 17 ALVIDNGSGM C KAGFAGDDAP   
2 217 EIVRDIKEKL C YVALDFEQEM   
3 257 VITIGNERFR C PEALFQPSFL   
4 272 FQPSFLGMES C GIHETTFNSI   
5 285 HETTFNSIMK C DVDIRKDLYA   
6 374 ESGPSIVHRK C F---------