Protein Name:
Transformer-2 protein homolog beta
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UniprotKB/SwissProt ID: P62996 (P62996)
Gene Name:
Tra2b
Organism: Mus musculus (Mouse)
Function: Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing (PubMed:28785060). Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P62996
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
118 |
VGNRANPDPN C CLGVFGLSLY |
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