Protein Name:
Profilin-1
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UniprotKB/SwissProt ID: P62962 (P62962)
Gene Name:
Pfn1
Organism: Mus musculus (Mouse)
Function: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P62962
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
128 |
GVHGGLINKK C YEMASHLRRS |
CCCHHHHHHH H HCCCCCCCEE |
3.57% |
22178444
24926564
21278135
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