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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
UniprotKB/SwissProt ID: P62880 (P62880)

Gene Name: Gnb2

Organism: Mus musculus (Mouse)

Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, perinuclear region. Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR020472 G-protein_beta_WD-40_rep
IPR001632 Gprotein_B
IPR016346 Guanine_nucleotide-bd_bsu
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR019775 WD40_repeat_CS
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt
The S-nitrosylation sites of P62880
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 148 ELPGHTGYLS C CRFLDDNQII  CHHHHHHHHH H HHHHHHHHHH  1.46% 22588120
2 149 LPGHTGYLSC C RFLDDNQIIT  CHHHHHHHHH H HHHHHHHHHH  2.87% 22588120
20925432
3 204 PDGRTFVSGA C DASIKLWDVR  CHHHHHHHHH H HHHHHHHHHH  5.25% 24895380
22588120
4 25 RNQIRDARKA C GDSTLTQITA  CHHHHHHHHH H HHHHHHHHHH  7.54% 24895380
22588120
20925432
5 250 AFTTGSDDAT C RLFDLRADQE  CHHHHHHHHH H HHHHHHHHHH  3.69% 24895380
6 317 VLAGHDNRVS C LGVTDDGMAV  CHHHHHHHHH H HHHHHHHHHH  3.33%