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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
UniprotKB/SwissProt ID: P62874 (P62874)

Gene Name: Gnb1

Organism: Mus musculus (Mouse)

Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR020472 G-protein_beta_WD-40_rep
IPR001632 Gprotein_B
IPR016346 Guanine_nucleotide-bd_bsu
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR019775 WD40_repeat_CS
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt
The S-nitrosylation sites of P62874
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 148 ELAGHTGYLS C CRFLDDNQIV  CCHHHHHHHH H HHHHHHHHHH  1.46% 24895380
22588120
2 149 LAGHTGYLSC C RFLDDNQIVT  CCHHHHHHHH H HHHHHHHHHH  2.87% 24895380
22588120
3 204 PDTRLFVSGA C DASAKLWDVR  CCHHHHHHHH H HHHHHHHHHH  5.25% 24895380
21278135
4 25 KNQIRDARKA C ADATLSQITN  CCHHHHHHHH H HHHHHHHHHH  3.85% 24895380
22588120
20925432
5 271 LMTYSHDNII C GITSVSFSKS  CCHHHHHHHH H HHHHHHHHHH  2.6%
6 294 LLLAGYDDFN C NVWDALKADR  CCHHHHHHHH H HHHHHHHHHH  4.36% 24895380
22588120
7 317 VLAGHDNRVS C LGVTDDGMAV  CCHHHHHHHH H HHHHHHHHHH  3.33% 21278135