Protein Name:
Ras-related protein Rap-1A
|
UniprotKB/SwissProt ID: P62836 (P62836)
Gene Name:
Rap1a
Organism: Rattus norvegicus (Rat)
Function: Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes (By similarity). Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. Facilitates the progressive accumulation of CDH1 at mature desmosome junctions via cAMP-dependent signaling and its interaction with PKP3 (By similarity). May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Cytoplasm, perinuclear region. Early endosome. Late endosome. Cytoplasm. Cell junction
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of P62836
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
139 |
EQGQNLARQW C NCAFLESSAK |
|
|
|
|
