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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Myotrophin

UniprotKB/SwissProt ID: P62775 (P62775)

Gene Name: Mtpn

Organism: Rattus norvegicus (Rat)

Function: Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer (By similarity). Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Cytoplasm, perinuclear region

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002110 Ankyrin_rpt
IPR036770 Ankyrin_rpt-contain_sf

The S-nitrosylation sites of P62775

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 83 LSAVYEGHVS C VKLLLSKGAD