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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Small ribosomal subunit protein eS6

UniprotKB/SwissProt ID: P62754 (P62754)

Gene Name: Rps6

Organism: Mus musculus (Mouse)

Function: Component of the 40S small ribosomal subunit. Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (PubMed:36517592). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001377 Ribosomal_eS6
IPR014401 Ribosomal_eS6-like
IPR018282 Ribosomal_eS6_CS

The S-nitrosylation sites of P62754

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 12 KLNISFPATG C QKLIEVDDER  CCCEEEECCC C CCEEEEECCH  2.54% 22178444
19483679
19101475
2 83 VRLLLSKGHS C YRPRRTGERK  CCCEEEECCC C CCEEEEECCH  2.5% 21278135