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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Small ribosomal subunit protein eS4

UniprotKB/SwissProt ID: P62703 (P62703)

Gene Name: Rps4x

Organism: Rattus norvegicus (Rat)

Function: Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR005824 KOW
IPR014722 Rib_uL2_dom2
IPR000876 Ribosomal_eS4
IPR032277 Ribosomal_eS4_C
IPR013845 Ribosomal_eS4_central_region
IPR038237 Ribosomal_eS4_central_sf
IPR041982 Ribosomal_eS4_KOW
IPR013843 Ribosomal_eS4_N
IPR018199 Ribosomal_eS4_N_CS
IPR002942 S4_RNA-bd
IPR036986 S4_RNA-bd_sf

The S-nitrosylation sites of P62703

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 41 PSTGPHKLRE C LPLIIFLRNR  CCCCCHHHHH H HHCCCCHHHH  3.71% 19101475