Protein Name:
CCHC-type zinc finger nucleic acid binding protein
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UniprotKB/SwissProt ID: P62633 (P62633)
Gene Name:
CNBP
Organism: Homo sapiens (Human)
Function: Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (PubMed:2562787). Has a role as transactivator of the Myc promoter (By similarity). Binds single-stranded RNA in a sequence-specific manner (By similarity) Binds G-rich elements in target mRNA coding sequences (PubMed:28329689). Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs (PubMed:28329689) Binds to RNA Binds to RNA Binds to RNA Binds to RNA Binds to RNA
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm. Endoplasmic reticulum. Cytoplasm. Cytoplasm. Cytoplasm. Cytoplasm. Cytoplasm. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P62633
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
101 |
KREREQCCYN C GKPGHLARDC |
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| 2 |
111 |
CGKPGHLARD C DHADEQKCYS |
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| 3 |
119 |
RDCDHADEQK C YSCGEFGHIQ |
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| 4 |
140 |
KDCTKVKCYR C GETGHVAINC |
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| 5 |
150 |
CGETGHVAIN C SKTSEVNCYR |
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| 6 |
158 |
INCSKTSEVN C YRCGESGHLA |
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| 7 |
161 |
SKTSEVNCYR C GESGHLAREC |
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| 8 |
171 |
CGESGHLARE C TIEATA---- |
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| 9 |
54 |
QFVSSSLPDI C YRCGESGHLA |
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| 10 |
57 |
SSSLPDICYR C GESGHLAKDC |
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| 11 |
67 |
CGESGHLAKD C DLQEDACYNC |
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| 12 |
74 |
AKDCDLQEDA C YNCGRGGHIA |
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| 13 |
77 |
CDLQEDACYN C GRGGHIAKDC |
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| 14 |
97 |
CKEPKREREQ C CYNCGKPGHL |
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