Protein Name:
Elongation factor 1-alpha 2
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UniprotKB/SwissProt ID: P62631 (P62631)
Gene Name:
Eef1a2
Organism: Mus musculus (Mouse)
Function: Translation elongation factor that catalyzes the GTP-dependent binding of aminoacyl-tRNA (aa-tRNA) to the A-site of ribosomes during the elongation phase of protein synthesis. Base pairing between the mRNA codon and the aa-tRNA anticodon promotes GTP hydrolysis, releasing the aa-tRNA from EEF1A1 and allowing its accommodation into the ribosome (By similarity). The growing protein chain is subsequently transferred from the P-site peptidyl tRNA to the A-site aa-tRNA, extending it by one amino acid through ribosome-catalyzed peptide bond formation (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P62631
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
111 |
NMITGTSQAD C AVLIVAAGVG |
CCCCCCEEEE E EEEECCCCCC |
2.94% |
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| 2 |
326 |
SVKDIRRGNV C GDSKADPPQE |
CCCCCCEEEE E EEEECCCCCC |
6.09% |
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| 3 |
370 |
VIDCHTAHIA C KFAELKEKID |
CCCCCCEEEE E EEEECCCCCC |
3.54% |
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| 4 |
411 |
IVEMVPGKPM C VESFSQYPPL |
CCCCCCEEEE E EEEECCCCCC |
4.1% |
21278135
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