\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: 26S proteasome regulatory subunit 10B

UniprotKB/SwissProt ID: P62334 (P62334)

Gene Name: Psmc6

Organism: Mus musculus (Mouse)

Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR050221 26S_Proteasome_ATPase
IPR003593 AAA+_ATPase
IPR041569 AAA_lid_3
IPR003959 ATPase_AAA_core
IPR003960 ATPase_AAA_CS
IPR012340 NA-bd_OB-fold
IPR027417 P-loop_NTPase
IPR032501 Prot_ATP_ID_OB_2nd

The S-nitrosylation sites of P62334

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 170 QRVGIIPPKG C LLYGPPGTGK  CCCHHHHHHH H HHHHHHHCHH  2.71%
2 193 LARAVASQLD C NFLKVVSSSI  CCCHHHHHHH H HHHHHHHCHH  5.43% 20925432
3 228 MFNYARDHQP C IIFMDEIDAI  CCCHHHHHHH H HHHHHHHCHH  2.76%
4 347 GFNGADLRNV C TEAGMFAIRA  CCCHHHHHHH H HHHHHHHCHH  3.04%