Protein Name:
ADP-ribosylation factor 6
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UniprotKB/SwissProt ID: P62332 (P62332)
Gene Name:
Arf6
Organism: Rattus norvegicus (Rat)
Function: GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (PubMed:26446845). Required for normal completion of mitotic cytokinesis. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension (PubMed:16672654). Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization. Regulates surface levels of adherens junction proteins such as CDH1. Required for NTRK1 sorting to the recycling pathway from early endosomes (PubMed:26446845)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol. Cell membrane. Endosome membrane. Recycling endosome membrane. Cell projection, filopodium membrane. Cell projection, ruffle. Cleavage furrow. Midbody, Midbody ring. Early endosome membrane. Golgi apparatus, trans-Golgi network membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P62332
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
90 |
GTQGLIFVVD C ADRDRIDEAR |
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