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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 14-3-3 protein epsilon

UniprotKB/SwissProt ID: P62259 (P62259)

Gene Name: Ywhae

Organism: Mus musculus (Mouse)

Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm. Melanosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000308 14-3-3
IPR023409 14-3-3_CS
IPR036815 14-3-3_dom_sf
IPR023410 14-3-3_domain

The S-nitrosylation sites of P62259

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 192 YEILNSPDRA C RLAKAAFDDA  CCHHHHHHHH H HHHHHHHHHH  3.69%
2 97 QMVETELKLI C CDILDVLDKH  CCHHHHHHHH H HHHHHHHHHH  2.18%
3 98 MVETELKLIC C DILDVLDKHL  CCHHHHHHHH H HHHHHHHHHH  2.64% 20925432