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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Small ribosomal subunit protein uS9

UniprotKB/SwissProt ID: P62249 (P62249)

Gene Name: RPS16

Organism: Homo sapiens (Human)

Function: Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR020568 Ribosomal_Su5_D2-typ_SF
IPR000754 Ribosomal_uS9
IPR020574 Ribosomal_uS9_CS
IPR014721 Ribsml_uS5_D2-typ_fold_subgr

The S-nitrosylation sites of P62249

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 127 RTLLVADPRR C ESKKFGGPGA  CCCCCCCCEE E EECCCCCEEH  7.95%
2 25 RKKTATAVAH C KRGNGLIKVN  CCCCCCCCEE E EECCCCCEEH  2.01% 2212679