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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Small ribosomal subunit protein uS8

UniprotKB/SwissProt ID: P62245 (P62245)

Gene Name: Rps15a

Organism: Mus musculus (Mouse)

Function: Component of the small ribosomal subunit (PubMed:36517592). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity). Required for proper erythropoiesis (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000630 Ribosomal_uS8
IPR047863 Ribosomal_uS8_CS
IPR035987 Ribosomal_uS8_sf

The S-nitrosylation sites of P62245

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 30 RGKRQVLIRP C SKVIVRFLTV  CCCHHHHHHH H HHCCHHHHHC  4.4% 21278135
2 72 VVNLTGRLNK C GVISPRFDVQ  CCCHHHHHHH H HHCCHHHHHC  5.25% 21278135