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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Small ribosomal subunit protein eS8

UniprotKB/SwissProt ID: P62241 (P62241)

Gene Name: RPS8

Organism: Homo sapiens (Human)

Function: Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Membrane. Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001047 Ribosomal_eS8
IPR018283 Ribosomal_eS8_CS
IPR042563 Ribosomal_protein_eS8_euk
IPR022309 Ribosomal_Se8/biogenesis_NSA2

The S-nitrosylation sites of P62241

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 100 LVRTKTLVKN C IVLIDSTPYR  CCCCCCCHHH C CCCCCCCCCC  1.56% 22178444
18335467
2212679
2 174 EQFQQGKLLA C IASRPGQCGR  CCCCCCCHHH C CCCCCCCCCC  2.42% 37478858
3 182 LACIASRPGQ C GRADGYVLEG  CCCCCCCHHH C CCCCCCCCCC  5.02% 37478858
4 71 DVGNFSWGSE C CTRKTRIIDV  CCCCCCCHHH C CCCCCCCCCC  2.84%
5 72 VGNFSWGSEC C TRKTRIIDVV  CCCCCCCHHH C CCCCCCCCCC  3.46%