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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ras-related protein R-Ras2

UniprotKB/SwissProt ID: P62070 (P62070)

Gene Name: RRAS2

Organism: Homo sapiens (Human)

Function: GTP-binding protein with GTPase activity involved in the regulation of MAPK signaling pathway, thereby controlling multiple cellular processes (PubMed:31130282). Involved in the regulation of MAPK signaling pathway (PubMed:31130282, PubMed:31130285). Regulation of craniofacial development (PubMed:31130282, PubMed:31130285)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Golgi apparatus membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd
IPR001806 Small_GTPase
IPR020849 Small_GTPase_Ras-type

The S-nitrosylation sites of P62070

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 183 RVIRKFQEQE C PPSPEPTRKE  CCCCCCCCCC C CCEEEEEEEC  6.33% 21278135
2 55 PTIEDSYTKQ C VIDDRAARLD  CCCCCCCCCC C CCEEEEEEEC  2.86% 21278135