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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ubiquitin carboxyl-terminal hydrolase 46

UniprotKB/SwissProt ID: P62069 (P62069)

Gene Name: Usp46

Organism: Mus musculus (Mouse)

Function: Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67 (PubMed:19465912). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2 (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR038765 Papain-like_cys_pep_sf
IPR050164 Peptidase_C19
IPR001394 Peptidase_C19_UCH
IPR018200 USP_CS
IPR028889 USP_dom