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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Nuclear transport factor 2

UniprotKB/SwissProt ID: P61971 (P61971)

Gene Name: Nutf2

Organism: Mus musculus (Mouse)

Function: Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Nucleus outer membrane. Nucleus, nuclear pore complex. Nucleus inner membrane. Nucleus, nucleoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR045875 NTF2
IPR032710 NTF2-like_dom_sf
IPR002075 NTF2_dom
IPR018222 Nuclear_transport_factor_2_euk

The S-nitrosylation sites of P61971

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 114 LLKNINDAWV C TNDMFRLALH  CCCCCHHHHH H HHHHHHHHHH  1.73%
2 38 QLGAIYIDAS C LTWEGQQFQG  CCCCCHHHHH H HHHHHHHHHH  4.15% 20925432
3 80 AQDHQPTPDS C IISMVVGQLK  CCCCCHHHHH H HHHHHHHHHH  4.11% 20925432