Protein Name:
DDB1- and CUL4-associated factor 7
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UniprotKB/SwissProt ID: P61962 (P61962)
Gene Name:
DCAF7
Organism: Homo sapiens (Human)
Function: Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P61962
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
109 |
RVGETETRLE C LLNNNKNSDF |
CCCCCCCCEE E EEECCEEEEE |
6.57% |
19483679
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| 2 |
256 |
EVVILDVRVP C TPVARLNNHR |
CCCCCCCCEE E EEECCEEEEE |
6.5% |
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| 3 |
61 |
GLDEESSEFI C RNTFDHPYPT |
CCCCCCCCEE E EEECCEEEEE |
3.13% |
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