Protein Name:
Beta-2-microglobulin
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UniprotKB/SwissProt ID: P61769 (P61769)
Gene Name:
B2M
Organism: Homo sapiens (Human)
Function: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted. Cell surface
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P61769
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
45 |
AENGKSNFLN C YVSGFHPSDI |
CCHHHHHHHH H HHHHCCHHHH |
3.74% |
25040305
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