Protein Name:
Small ribosomal subunit protein eS1
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UniprotKB/SwissProt ID: P61247 (P61247)
Gene Name:
RPS3A
Organism: Homo sapiens (Human)
Function: Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Nucleus, nucleolus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P61247
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
111 |
HGMDLTRDKM C SMVKKWQTMI |
CCCCCCCCCC C CCCCCCCCCC |
2.67% |
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| 2 |
139 |
TTDGYLLRLF C VGFTKKRNNQ |
CCCCCCCCCC C CCCCCCCCCC |
3.28% |
19483679
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| 3 |
201 |
DSIGKDIEKA C QSIYPLHDVF |
CCCCCCCCCC C CCCCCCCCCC |
4.89% |
22178444
19483679
18335467
37478858
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| 4 |
96 |
LITEDVQGKN C LTNFHGMDLT |
CCCCCCCCCC C CCCCCCCCCC |
5.89% |
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