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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: ADP-ribosylation factor-like protein 1

UniprotKB/SwissProt ID: P61212 (P61212)

Gene Name: Arl1

Organism: Rattus norvegicus (Rat)

Function: GTP-binding protein. Can activate phospholipase D with very low efficiency (By similarity). Important for normal function of the Golgi apparatus GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Golgi apparatus membrane. Golgi apparatus, trans-Golgi network membrane. Membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd
IPR024156 Small_GTPase_ARF
IPR006689 Small_GTPase_ARF/SAR

The S-nitrosylation sites of P61212

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 80 GQTSIRPYWR C YYSNTDAVIY