Protein Name:
Ubiquitin-conjugating enzyme E2 D1
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UniprotKB/SwissProt ID: P61080 (P61080)
Gene Name:
Ube2d1
Organism: Mus musculus (Mouse)
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P61080
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
111 |
KVLLSICSLL C DPNPDDPLVP |
CHHHHHHHHH H HHHHCCCCCC |
11.23% |
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| 2 |
85 |
HPNINSNGSI C LDILRSQWSP |
CHHHHHHHHH H HHHHCCCCCC |
2.75% |
22178444
19101475
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