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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Destrin

UniprotKB/SwissProt ID: P60981 (P60981)

Gene Name: DSTN

Organism: Homo sapiens (Human)

Function: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002108 ADF-H
IPR029006 ADF-H/Gelsolin-like_dom_sf
IPR017904 ADF/Cofilin

The S-nitrosylation sites of P60981

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 12 ASGVQVADEV C RIFYDMKVRK  CCCCCCHHHH H HHHHHCCCCC  2.31%
2 135 KKKFQGIKHE C QANGPEDLNR  CCCCCCHHHH H HHHHHCCCCC  4.65% 22126794
2212679
37478858
3 147 ANGPEDLNRA C IAEKLGGSLI  CCCCCCHHHH H HHHHHCCCCC  2.46% 19483679
4 163 GGSLIVAFEG C PV--------  CCCCCCHHHH H HHHHHCCCCC  2.1%
5 23 RIFYDMKVRK C STPEEIKKRK  CCCCCCHHHH H HHHHHCCCCC  3.72%
6 39 IKKRKKAVIF C LSADKKCIIV  CCCCCCHHHH H HHHHHCCCCC  1.7% 37478858
7 46 VIFCLSADKK C IIVEEGKEIL  CCCCCCHHHH H HHHHHCCCCC  2.94%
8 80 HFVGMLPEKD C RYALYDASFE  CCCCCCHHHH H HHHHHCCCCC  5.47%