Protein Name:
Ras-related C3 botulinum toxin substrate 3
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UniprotKB/SwissProt ID: P60763 (P60763)
Gene Name:
RAC3
Organism: Homo sapiens (Human)
Function: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Endomembrane system. Cell projection, lamellipodium. Cytoplasm, perinuclear region. Cell membrane. Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P60763
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
157 |
REIGSVKYLE C SALTQRGLKT |
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37478858
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| 2 |
178 |
VFDEAIRAVL C PPPVKKPGKK |
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| 3 |
6 |
-----MQAIK C VVVGDGAVGK |
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| 4 |
81 |
SYPQTDVFLI C FSLVSPASFE |
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