Protein Name:
Actin, cytoplasmic 1
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UniprotKB/SwissProt ID: P60711 (P60711)
Gene Name:
Actb
Organism: Rattus norvegicus (Rat)
Function: Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (By similarity). Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction (By similarity). In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA (By similarity). Plays a role in the assembly of the gamma-tubulin ring complex (gTuRC), which regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments (By similarity). Part of the ACTR1A/ACTB filament around which the dynactin complex is built (By similarity). The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P60711
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
217 |
EIVRDIKEKL C YVALDFEQEM |
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| 2 |
285 |
HETTFNSIMK C DVDIRKDLYA |
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| 3 |
374 |
ESGPSIVHRK C F--------- |
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