Protein Name:
Ubiquitin-conjugating enzyme E2 G2
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UniprotKB/SwissProt ID: P60605 (P60605)
Gene Name:
Ube2g2
Organism: Mus musculus (Mouse)
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum. Lipid droplet
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Graphical Visualization of S-nitrosylation Sites:
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