Protein Name:
Triosephosphate isomerase
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UniprotKB/SwissProt ID: P60174 (P60174)
Gene Name:
TPI1
Organism: Homo sapiens (Human)
Function: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P60174
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
127 |
ALAEGLGVIA C IGEKLDEREA |
CCCCCCCCEE E EEEEHHCCCC |
12.22% |
37478858
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| 2 |
218 |
IYGGSVTGAT C KELASQPDVD |
CCCCCCCCEE E EEEEHHCCCC |
46.33% |
19483679
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| 3 |
42 |
AKVPADTEVV C APPTAYIDFA |
CCCCCCCCEE E EEEEHHCCCC |
38.45% |
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| 4 |
67 |
DPKIAVAAQN C YKVTNGAFTG |
CCCCCCCCEE E EEEEHHCCCC |
37.38% |
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| 5 |
87 |
GEISPGMIKD C GATWVVLGHS |
CCCCCCCCEE E EEEEHHCCCC |
20.62% |
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