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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: FXYD domain-containing ion transport regulator 7

UniprotKB/SwissProt ID: P59648 (P59648)

Gene Name: Fxyd7

Organism: Mus musculus (Mouse)

Function: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane (PubMed:12093728, PubMed:15133029, PubMed:16269407). Reduces the apparent affinity for external K(+), an effect that depends on the presence of external Na(+) and voltage (PubMed:12093728, PubMed:15133029). Increases the apparent affinity for intracellular Na(+) (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR047284 FXYD7
IPR047297 FXYD_motif
IPR000272 Ion-transport_regulator_FXYD

The S-nitrosylation sites of P59648

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 66 SRSESPTCKS C KSELPSSAPG