UniprotKB/SwissProt ID: P56656 (P56656)
Gene Name:
Cyp2c39
Organism: Mus musculus (Mouse)
Function: A cytochrome P450 monooxygenase that primarily catalyzes the epoxidation of 11,12 and 14,15 double bonds of (5Z,8Z,11Z,14Z)-eicosatetraenoic acid (arachidonate) forming 11,12- and 14,15-epoxyeicosatrienoic acids (11,12- and 14,15-EET) regioisomers. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH--hemoprotein reductase)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Microsome membrane
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