Protein Name:
Cytochrome P450 2C37
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UniprotKB/SwissProt ID: P56654 (P56654)
Gene Name:
Cyp2c37
Organism: Mus musculus (Mouse)
Function: A cytochrome P450 monooxygenase that metabolizes (5Z,8Z,11Z,14Z)-eicosatetraenoic acid (arachidonate) to primarily produce 12-hydroxyeicosatetraenoic acid (12-HETE). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH--hemoprotein reductase)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Microsome membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P56654
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
151 |
IEDRVQEEAR C LVEELRKTNG |
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| 2 |
435 |
FIPFSTGKRI C AGEGLARMEL |
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| 3 |
51 |
NILQIDVKDI C QSFTNLSKVY |
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