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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Isocitrate dehydrogenase [NADP], mitochondrial

UniprotKB/SwissProt ID: P56574 (P56574)

Gene Name: Idh2

Organism: Rattus norvegicus (Rat)

Function: Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR019818 IsoCit/isopropylmalate_DH_CS
IPR004790 Isocitrate_DH_NADP
IPR024084 IsoPropMal-DH-like_dom

The S-nitrosylation sites of P56574

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 113 ATQKYSVAVK C ATITPDEARV   
2 154 GGTVFREPII C KNIPRLVPGW   
3 308 LKSSGGFVWA C KNYDGDVQSD   
4 402 IRFAQTLEKV C VQTVESGAMT   
5 418 SGAMTKDLAG C IHGLSNVKLN