Protein Name:
Deoxyribonuclease-2-alpha
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UniprotKB/SwissProt ID: P56542 (P56542)
Gene Name:
Dnase2
Organism: Mus musculus (Mouse)
Function: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the clearance of nucleic acids generated through apoptosis, hence preventing autoinflammation. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver and bone marrow, where it degrades nuclear DNA expelled from erythroid precursor cells
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Lysosome
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Graphical Visualization of S-nitrosylation Sites:
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