Protein Name:
Putative mitochondrial transporter UCP3
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UniprotKB/SwissProt ID: P56501 (P56501)
Gene Name:
Ucp3
Organism: Mus musculus (Mouse)
Function: Putative transmembrane transporter that plays a role in mitochondrial metabolism via an as yet unclear mechanism (PubMed:10748195, PubMed:10748196). Originally, this mitochondrial protein was thought to act as a proton transmembrane transporter from the mitochondrial intermembrane space into the matrix, causing proton leaks through the inner mitochondrial membrane, thereby uncoupling mitochondrial membrane potential generation from ATP synthesis (PubMed:29212043). However, this function is controversial and uncoupling may not be the function, or at least not the main function, but rather a consequence of more conventional metabolite transporter activity (PubMed:11707458, PubMed:20363757)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P56501
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
25 |
VKFLGAGTAA C FADLLTFPLD |
CCCCCCCCCC C CCEEEECCCH |
2.4% |
21278135
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