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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Myc-associated zinc finger protein

UniprotKB/SwissProt ID: P56270 (P56270)

Gene Name: MAZ

Organism: Homo sapiens (Human)

Function: Transcriptional regulator, potentially with dual roles in transcription initiation and termination Binds DNA and functions as a transcriptional activator (PubMed:12270922). Binds to two G/A-rich sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former (PubMed:1502157). Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors (PubMed:1502157) Binds DNA and functions as a transcriptional activator (PubMed:12270922). Inhibits MAZ isoform 1-mediated transcription (PubMed:12270922) Binds DNA and functions as a transcriptional activator

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

The S-nitrosylation sites of P56270

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 309 LSHSDEKPYQ C PVCQQRFKRK