Protein Name:
Puromycin-sensitive aminopeptidase
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UniprotKB/SwissProt ID: P55786 (P55786)
Gene Name:
NPEPPS
Organism: Homo sapiens (Human)
Function: Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P55786
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
190 |
EATDARRAFP C WDEPAIKATF |
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| 2 |
265 |
FVETRSKDGV C VRVYTPVGKA |
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| 3 |
527 |
RLLRLSQKKF C AGGSYVGEDC |
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| 4 |
66 |
ADVSPINYSL C LKPDLLDFTF |
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| 5 |
888 |
PSAERTIQQC C ENILLNAAWL |
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