UniprotKB/SwissProt ID: P55196 (P55196)
Gene Name:
AFDN
Organism: Homo sapiens (Human)
Function: Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs) (By similarity). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton (PubMed:11024295). May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions (PubMed:30463011)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell junction, adherens junction
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