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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Nck-associated protein 1

UniprotKB/SwissProt ID: P55161 (P55161)

Gene Name: Nckap1

Organism: Rattus norvegicus (Rat)

Function: Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1 (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Cell projection, lamellipodium membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR019137 Nck-associated_protein-1

The S-nitrosylation sites of P55161

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 556 SRAFEKMFQQ C LELPSQSRYS   
2 599 HHIGDRSLSL C NMFLDEMAKQ