Protein Name:
Probable ATP-dependent RNA helicase DDX6
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UniprotKB/SwissProt ID: P54823 (P54823)
Gene Name:
Ddx6
Organism: Mus musculus (Mouse)
Function: Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions (By similarity). Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation (By similarity). In the process of mRNA degradation, plays a role in mRNA decapping (By similarity). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts (PubMed:26098573)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, P-body. Cytoplasm. Nucleus. Cytoplasm, Cytoplasmic ribonucleoprotein granule
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P54823
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
324 |
AYVTERQKVH C LNTLFSRLQI |
CCCCCCCCCE E EEEECCCCCC |
3.34% |
20925432
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