Protein Name:
Adenylate kinase 2, mitochondrial
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UniprotKB/SwissProt ID: P54819 (P54819)
Gene Name:
AK2
Organism: Homo sapiens (Human)
Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion intermembrane space
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P54819
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
232 |
SILAAFSKAT C KDLVMFI--- |
CCCCCCCCCC C CCCCEEEEEE |
3.74% |
24105792
|
| 2 |
40 |
TQAPRLAENF C VCHLATGDML |
CCCCCCCCCC C CCCCEEEEEE |
4.87% |
24105792
|
| 3 |
42 |
APRLAENFCV C HLATGDMLRA |
CCCCCCCCCC C CCCCEEEEEE |
1.98% |
24105792
25040305
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| 4 |
92 |
LIEKNLETPL C KNGFLLDGFP |
CCCCCCCCCC C CCCCEEEEEE |
3.2% |
19483679
24105792
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