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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Peptide methionine sulfoxide reductase A4, chloroplastic

UniprotKB/SwissProt ID: P54150 (P54150)

Gene Name: MSR4

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins. Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation. Prevents the methionine sulfoxidation of the heat shock protein HSP21 and its subsequent inactivation. MSRA family specifically reduces the MetSO S-enantiomer

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Plastid, chloroplast stroma

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002569 Met_Sox_Rdtase_MsrA_dom
IPR036509 Met_Sox_Rdtase_MsrA_sf
IPR050162 MsrA_MetSO_reductase

The S-nitrosylation sites of P54150

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 135 IVHNPSYEDV C TGTTGHNEVV