Protein Name:
CCHC-type zinc finger nucleic acid binding protein
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UniprotKB/SwissProt ID: P53996 (P53996)
Gene Name:
Cnbp
Organism: Mus musculus (Mouse)
Function: Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (By similarity). Has a role as transactivator of the Myc promoter (PubMed:12706888). Binds single-stranded RNA in a sequence-specific manner (By similarity). Binds G-rich elements in target mRNA coding sequences (By similarity). Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm. Endoplasmic reticulum
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P53996
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
120 |
RDCDHADEQK C YSCGEFGHIQ |
CCCCCCCCCC C CCCCCCCCCC |
2.78% |
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| 2 |
141 |
KDCTKVKCYR C GETGHVAINC |
CCCCCCCCCC C CCCCCCCCCC |
2.03% |
24926564
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| 3 |
159 |
INCSKTSEVN C YRCGESGHLA |
CCCCCCCCCC C CCCCCCCCCC |
2.47% |
21278135
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| 4 |
162 |
SKTSEVNCYR C GESGHLAREC |
CCCCCCCCCC C CCCCCCCCCC |
2.61% |
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| 5 |
172 |
CGESGHLARE C TIEATA---- |
CCCCCCCCCC C CCCCCCCCCC |
3.75% |
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| 6 |
88 |
CGRGGHIAKD C KEPKREREQC |
CCCCCCCCCC C CCCCCCCCCC |
5.46% |
21278135
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| 7 |
98 |
CKEPKREREQ C CYNCGKPGHL |
CCCCCCCCCC C CCCCCCCCCC |
1.97% |
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| 8 |
99 |
KEPKREREQC C YNCGKPGHLA |
CCCCCCCCCC C CCCCCCCCCC |
2.46% |
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