Protein Name:
Ras-related protein Rab-2A
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UniprotKB/SwissProt ID: P53994 (P53994)
Gene Name:
Rab2a
Organism: Mus musculus (Mouse)
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Required for protein transport from the endoplasmic reticulum to the Golgi complex. Regulates the compacted morphology of the Golgi (Probable). Together with RAB2B redundantly required for efficient autophagic flux (PubMed:28063257)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum-Golgi intermediate compartment membrane. Melanosome. Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasmic vesicle, secretory vesicle, acrosome. Cytoplasmic vesicle, autophagosome membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P53994
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
21 |
IIGDTGVGKS C LLLQFTDKRF |
CCHHEEEEEE E ECCCCCCHHH |
3.37% |
20925432
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