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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Clathrin heavy chain 2

UniprotKB/SwissProt ID: P53675 (P53675)

Gene Name: CLTCL1

Organism: Homo sapiens (Human)

Function: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasmic vesicle membrane. Membrane, coated pit

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016024 ARM-type_fold
IPR055358 CHCR
IPR000547 Clathrin_H-chain/VPS_repeat
IPR015348 Clathrin_H-chain_linker_core
IPR016025 Clathrin_H-chain_N
IPR022365 Clathrin_H-chain_propeller_rpt
IPR016341 Clathrin_heavy_chain
IPR011990 TPR-like_helical_dom_sf

The S-nitrosylation sites of P53675

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1528 NNWWAQSVEL C KKDHLYKDAM   
2 617 HYDRAHIAQL C EKAGLLQQAL   
3 736 DVHLKYIQAA C KTGQIKEVER   
4 778 LTDQLPLIIV C DRFGFVHDLV   
5 892 IYIDSNNSPE C FLRENAYYDS   
6 918 YCEKRDPHLA C VAYERGQCDL    37478858